Spontaneous resolution of lupus nephritis following withdrawal of etanercept.

نویسندگان

  • Taher M Yahya
  • Susmitha Dhanyamraju
  • Thomas M Harrington
  • Jeffrey W Prichard
چکیده

INTRODUCTION Etanercept, a systemic inhibitor of α-TNF, is used for treatment of various autoimmune disorders. We report a case of spontaneous resolution of etanercept-induced lupus nephritis. CASE DESCRIPTION A 57-year-old female patient taking etanercept for psoriasis presented with laboratory-and histology-confirmed lupus nephritis. After stopping etanercept, there was normalization of proteinuria, hematuria, serum complements, anti-dsDNA antibody, and resolution of the acute glomerular inflammatory process on repeat kidney biopsy. CONCLUSION This case demonstrates serology- and biopsy-confirmed resolution of active lupus nephritis upon withdrawal of etanercept.

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عنوان ژورنال:
  • Annals of clinical and laboratory science

دوره 43 4  شماره 

صفحات  -

تاریخ انتشار 2013